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Keratinocyte-mediated activation of the cytokine TGFβ maintains skin-recirculating memory CD8(+) T cells

Regulated activation of the cytokine TGFβ by integrins α(v)β(6) and α(v)β(8) expressed on keratinocytes is required for residence of epidermal-resident memory T cells, but whether skin-derived signals also affect recirculating memory cells in the skin remains unclear. Here, we show that after resolu...

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Detalhes bibliográficos
Publicado no:Immunity
Main Authors: Hirai, Toshiro, Zenke, Yukari, Yang, Yi, Bartholin, Laurent, Beura, Lalit K., Masopust, David, Kaplan, Daniel H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6531326/
https://ncbi.nlm.nih.gov/pubmed/30952606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2019.03.002
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