Selective head cooling during neonatal seizures prevents postictal cerebral vascular dysfunction without reducing epileptiform activity

Epileptic seizures in neonates cause cerebrovascular injury and impairment of cerebral blood flow (CBF) regulation. In the bicuculline model of seizures in newborn pigs, we tested the hypothesis that selective head cooling prevents deleterious effects of seizures on cerebral vascular functions. Prev...

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Gepubliceerd in:Am J Physiol Heart Circ Physiol
Hoofdauteurs: Harsono, Mimily, Pourcyrous, Massroor, Jolly, Elliott J., de Jongh Curry, Amy, Fedinec, Alexander L., Liu, Jianxiong, Basuroy, Shyamali, Zhuang, Daming, Leffler, Charles W., Parfenova, Helena
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2016
Onderwerpen:
Vascular Biology and Microcirculation
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130497/
https://ncbi.nlm.nih.gov/pubmed/27591217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00227.2016
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