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Antioxidant roles of heme oxygenase, carbon monoxide, and bilirubin in cerebral circulation during seizures

Postictal cerebrovascular dysfunction is an adverse effect of seizures in newborn piglets. The brain heme oxygenase (HO) provides protection against cerebrovascular dysfunction. We investigated the contribution of reactive oxygen species (ROS) to seizure-induced vascular damage and the mechanism of...

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Detalhes bibliográficos
Main Authors: Parfenova, Helena, Leffler, Charles W, Basuroy, Shyamali, Liu, Jianxiong, Fedinec, Alexander L
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367218/
https://ncbi.nlm.nih.gov/pubmed/22354150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.13
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