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Antioxidant roles of heme oxygenase, carbon monoxide, and bilirubin in cerebral circulation during seizures

Postictal cerebrovascular dysfunction is an adverse effect of seizures in newborn piglets. The brain heme oxygenase (HO) provides protection against cerebrovascular dysfunction. We investigated the contribution of reactive oxygen species (ROS) to seizure-induced vascular damage and the mechanism of...

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書誌詳細
主要な著者: Parfenova, Helena, Leffler, Charles W, Basuroy, Shyamali, Liu, Jianxiong, Fedinec, Alexander L
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367218/
https://ncbi.nlm.nih.gov/pubmed/22354150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2012.13
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