Astrocyte-produced carbon monoxide and the carbon monoxide donor CORM-A1 protect against cerebrovascular dysfunction caused by prolonged neonatal asphyxia

Neonatal asphyxia leads to cerebrovascular disease and neurological complications via a mechanism that may involve oxidative stress. Carbon monoxide (CO) is an antioxidant messenger produced via a heme oxygenase (HO)-catalyzed reaction. Cortical astrocytes are the major cells in the brain that expre...

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Publicado en:Am J Physiol Heart Circ Physiol
Autores principales: Parfenova, Helena, Pourcyrous, Massroor, Fedinec, Alex L., Liu, Jianxiong, Basuroy, Shyamali, Leffler, Charles W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6230909/
https://ncbi.nlm.nih.gov/pubmed/30028198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00140.2018
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