Selective head cooling during neonatal seizures prevents postictal cerebral vascular dysfunction without reducing epileptiform activity

Epileptic seizures in neonates cause cerebrovascular injury and impairment of cerebral blood flow (CBF) regulation. In the bicuculline model of seizures in newborn pigs, we tested the hypothesis that selective head cooling prevents deleterious effects of seizures on cerebral vascular functions. Prev...

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Опубликовано в: :Am J Physiol Heart Circ Physiol
Главные авторы: Harsono, Mimily, Pourcyrous, Massroor, Jolly, Elliott J., de Jongh Curry, Amy, Fedinec, Alexander L., Liu, Jianxiong, Basuroy, Shyamali, Zhuang, Daming, Leffler, Charles W., Parfenova, Helena
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2016
Предметы:
Vascular Biology and Microcirculation
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130497/
https://ncbi.nlm.nih.gov/pubmed/27591217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00227.2016
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