Selective head cooling during neonatal seizures prevents postictal cerebral vascular dysfunction without reducing epileptiform activity

Epileptic seizures in neonates cause cerebrovascular injury and impairment of cerebral blood flow (CBF) regulation. In the bicuculline model of seizures in newborn pigs, we tested the hypothesis that selective head cooling prevents deleterious effects of seizures on cerebral vascular functions. Prev...

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Detalhes bibliográficos
Publicado no:Am J Physiol Heart Circ Physiol
Main Authors: Harsono, Mimily, Pourcyrous, Massroor, Jolly, Elliott J., de Jongh Curry, Amy, Fedinec, Alexander L., Liu, Jianxiong, Basuroy, Shyamali, Zhuang, Daming, Leffler, Charles W., Parfenova, Helena
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Vascular Biology and Microcirculation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5130497/
https://ncbi.nlm.nih.gov/pubmed/27591217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00227.2016
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