Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis

Certain secretory proteins are known to be critical for maintaining the stemness of stem cells through autocrine signaling. However, the processes underlying the biogenesis, maturation, and secretion of these proteins remain largely unknown. Here we demonstrate that many secretory proteins produced...

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Bibliografske podrobnosti
izdano v:J Clin Invest
Main Authors: Gu, Hao, Chen, Chiqi, Hao, Xiaoxin, Wang, Conghui, Zhang, Xiaocui, Li, Zhen, Shao, Hongfang, Zeng, Hongxiang, Yu, Zhuo, Xie, Li, Xia, Fangzhen, Zhang, Feifei, Liu, Xiaoye, Zhang, Yaping, Jiang, Haishan, Zhu, Jun, Wan, Jiangbo, Wang, Chun, Weng, Wei, Xie, Jingjing, Tao, Minfang, Zhang, Cheng Cheng, Liu, Junling, Chen, Guo-Qiang, Zheng, Junke
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2016
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127665/
https://ncbi.nlm.nih.gov/pubmed/27797340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI87105
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