Sorting protein VPS33B regulates exosomal autocrine signaling to mediate hematopoiesis and leukemogenesis

Certain secretory proteins are known to be critical for maintaining the stemness of stem cells through autocrine signaling. However, the processes underlying the biogenesis, maturation, and secretion of these proteins remain largely unknown. Here we demonstrate that many secretory proteins produced...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Gu, Hao, Chen, Chiqi, Hao, Xiaoxin, Wang, Conghui, Zhang, Xiaocui, Li, Zhen, Shao, Hongfang, Zeng, Hongxiang, Yu, Zhuo, Xie, Li, Xia, Fangzhen, Zhang, Feifei, Liu, Xiaoye, Zhang, Yaping, Jiang, Haishan, Zhu, Jun, Wan, Jiangbo, Wang, Chun, Weng, Wei, Xie, Jingjing, Tao, Minfang, Zhang, Cheng Cheng, Liu, Junling, Chen, Guo-Qiang, Zheng, Junke
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5127665/
https://ncbi.nlm.nih.gov/pubmed/27797340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI87105
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