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Targeting mutant RAS in patient-derived colorectal cancer organoids by combinatorial drug screening
Colorectal cancer (CRC) organoids can be derived from almost all CRC patients and therefore capture the genetic diversity of this disease. We assembled a panel of CRC organoids carrying either wild-type or mutant RAS, as well as normal organoids and tumor organoids with a CRISPR-introduced oncogenic...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | eLife |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
eLife Sciences Publications, Ltd
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5127645/ https://ncbi.nlm.nih.gov/pubmed/27845624 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.18489 |
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