The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies

The glycoprotein of Ebola virus (EBOV GP), a member of the family Filoviridae, facilitates viral entry into target cells. In addition, EBOV GP antagonizes the antiviral activity of the host cell protein tetherin, which may otherwise restrict EBOV release from infected cells. However, it is unclear h...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Virol
Päätekijät: Brinkmann, Constantin, Nehlmeier, Inga, Walendy-Gnirß, Kerstin, Nehls, Julia, González Hernández, Mariana, Hoffmann, Markus, Qiu, Xiangguo, Takada, Ayato, Schindler, Michael, Pöhlmann, Stefan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2016
Aiheet:
Virus-Cell Interactions
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126366/
https://ncbi.nlm.nih.gov/pubmed/27707924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01563-16
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