The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies

The glycoprotein of Ebola virus (EBOV GP), a member of the family Filoviridae, facilitates viral entry into target cells. In addition, EBOV GP antagonizes the antiviral activity of the host cell protein tetherin, which may otherwise restrict EBOV release from infected cells. However, it is unclear h...

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Bibliografische gegevens
Gepubliceerd in:J Virol
Hoofdauteurs: Brinkmann, Constantin, Nehlmeier, Inga, Walendy-Gnirß, Kerstin, Nehls, Julia, González Hernández, Mariana, Hoffmann, Markus, Qiu, Xiangguo, Takada, Ayato, Schindler, Michael, Pöhlmann, Stefan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2016
Onderwerpen:
Virus-Cell Interactions
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126366/
https://ncbi.nlm.nih.gov/pubmed/27707924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01563-16
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