The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies

The glycoprotein of Ebola virus (EBOV GP), a member of the family Filoviridae, facilitates viral entry into target cells. In addition, EBOV GP antagonizes the antiviral activity of the host cell protein tetherin, which may otherwise restrict EBOV release from infected cells. However, it is unclear h...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Brinkmann, Constantin, Nehlmeier, Inga, Walendy-Gnirß, Kerstin, Nehls, Julia, González Hernández, Mariana, Hoffmann, Markus, Qiu, Xiangguo, Takada, Ayato, Schindler, Michael, Pöhlmann, Stefan
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126366/
https://ncbi.nlm.nih.gov/pubmed/27707924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01563-16
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