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Analysis of Determinants in Filovirus Glycoproteins Required for Tetherin Antagonism

The host cell protein tetherin can restrict the release of enveloped viruses from infected cells. The HIV-1 protein Vpu counteracts tetherin by removing it from the site of viral budding, the plasma membrane, and this process depends on specific interactions between the transmembrane domains of Vpu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gnirß, Kerstin, Fiedler, Marie, Krämer-Kühl, Annika, Bolduan, Sebastian, Mittler, Eva, Becker, Stephan, Schindler, Michael, Pöhlmann, Stefan
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014715/
https://ncbi.nlm.nih.gov/pubmed/24721789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v6041654
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