The Tetherin Antagonism of the Ebola Virus Glycoprotein Requires an Intact Receptor-Binding Domain and Can Be Blocked by GP1-Specific Antibodies

The glycoprotein of Ebola virus (EBOV GP), a member of the family Filoviridae, facilitates viral entry into target cells. In addition, EBOV GP antagonizes the antiviral activity of the host cell protein tetherin, which may otherwise restrict EBOV release from infected cells. However, it is unclear h...

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Библиографические подробности
Опубликовано в: :J Virol
Главные авторы: Brinkmann, Constantin, Nehlmeier, Inga, Walendy-Gnirß, Kerstin, Nehls, Julia, González Hernández, Mariana, Hoffmann, Markus, Qiu, Xiangguo, Takada, Ayato, Schindler, Michael, Pöhlmann, Stefan
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2016
Предметы:
Virus-Cell Interactions
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5126366/
https://ncbi.nlm.nih.gov/pubmed/27707924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01563-16
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