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Absolute Amounts and Status of the Nrf2-Keap1-Cul3 Complex within Cells
The transcription factor Nrf2 (NF-E2-related-factor 2) is essential for the oxidative and electrophilic stress responses. Keap1 (Kelch-like-ECH-associated-protein 1), an adaptor for a cullin-3 (Cul3)-based ubiquitin ligase, regulates Nrf2 activity through proteasomal degradation, and acts as a senso...
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| Publicado en: | Mol Cell Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5126296/ https://ncbi.nlm.nih.gov/pubmed/27697860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00389-16 |
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