Characterizations of Three Major Cysteine Sensors of Keap1 in Stress Response

The Keap1-Nrf2 system plays a central role in cytoprotection against electrophilic/oxidative stresses. Although Cys151, Cys273, and Cys288 of Keap1 are major sensor cysteine residues for detecting these stresses, it has not been technically feasible to evaluate the functionality of Cys273 or Cys288,...

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Gepubliceerd in:Mol Cell Biol
Hoofdauteurs: Saito, Ryota, Suzuki, Takafumi, Hiramoto, Keiichiro, Asami, Soichiro, Naganuma, Eriko, Suda, Hiromi, Iso, Tatsuro, Yamamoto, Hirotaka, Morita, Masanobu, Baird, Liam, Furusawa, Yuki, Negishi, Takaaki, Ichinose, Masakazu, Yamamoto, Masayuki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2016
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Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719294/
https://ncbi.nlm.nih.gov/pubmed/26527616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00868-15
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