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The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway
The KEAP1-NRF2 pathway is the principal protective response to oxidative and electrophilic stresses. Under homeostatic conditions, KEAP1 forms part of an E3 ubiquitin ligase, which tightly regulates the activity of the transcription factor NRF2 by targeting it for ubiquitination and proteasome-depen...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Mol Cell Biol |
|---|---|
| Prif Awduron: | , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Society for Microbiology
2020
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7296212/ https://ncbi.nlm.nih.gov/pubmed/32284348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00099-20 |
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