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Stress-sensing mechanisms and the physiological roles of the Keap1–Nrf2 system during cellular stress

Transcription factor Nrf2 (NF-E2-related factor 2) is a master regulator of cellular responses against environmental stresses. Nrf2 induces the expression of detoxification and antioxidant enzymes and suppresses the induction of pro-inflammatory cytokine genes. Keap1 (Kelch-like ECH-associated prote...

詳細記述

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書誌詳細
出版年:J Biol Chem
主要な著者: Suzuki, Takafumi, Yamamoto, Masayuki
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Biochemistry and Molecular Biology 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5641889/
https://ncbi.nlm.nih.gov/pubmed/28842501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R117.800169
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