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Stress-sensing mechanisms and the physiological roles of the Keap1–Nrf2 system during cellular stress
Transcription factor Nrf2 (NF-E2-related factor 2) is a master regulator of cellular responses against environmental stresses. Nrf2 induces the expression of detoxification and antioxidant enzymes and suppresses the induction of pro-inflammatory cytokine genes. Keap1 (Kelch-like ECH-associated prote...
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| Udgivet i: | J Biol Chem |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5641889/ https://ncbi.nlm.nih.gov/pubmed/28842501 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R117.800169 |
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