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The Molecular Mechanisms Regulating the KEAP1-NRF2 Pathway
The KEAP1-NRF2 pathway is the principal protective response to oxidative and electrophilic stresses. Under homeostatic conditions, KEAP1 forms part of an E3 ubiquitin ligase, which tightly regulates the activity of the transcription factor NRF2 by targeting it for ubiquitination and proteasome-depen...
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| Pubblicato in: | Mol Cell Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7296212/ https://ncbi.nlm.nih.gov/pubmed/32284348 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00099-20 |
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