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Fluorescence‐ and bioluminescence‐based approaches to study GPCR ligand binding

Ligand binding is a vital component of any pharmacologist's toolbox and allows the detailed investigation of how a molecule binds to its receptor. These studies enable the experimental determination of binding affinity of labelled and unlabelled compounds through kinetic, saturation (K(d)) and...

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書目詳細資料
發表在:Br J Pharmacol
Main Authors: Stoddart, Leigh A, White, Carl W, Nguyen, Kim, Hill, Stephen J, Pfleger, Kevin D G
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2015
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5125978/
https://ncbi.nlm.nih.gov/pubmed/26317175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13316
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