Ligand-directed covalent labelling of a GPCR with a fluorescent tag in live cells

To study the localisation of G protein-coupled receptors (GPCR) in their native cellular environment requires their visualisation through fluorescent labelling. To overcome the requirement for genetic modification of the receptor or the limitations of dissociable fluorescent ligands, here we describ...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Stoddart, Leigh A., Kindon, Nicholas D., Otun, Omolade, Harwood, Clare R., Patera, Foteini, Veprintsev, Dmitry B., Woolard, Jeanette, Briddon, Stephen J., Franks, Hester A., Hill, Stephen J., Kellam, Barrie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7695831/
https://ncbi.nlm.nih.gov/pubmed/33247190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-01451-w
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