Endogenous DKK1 and FRZB Regulate Chondrogenesis and Hypertrophy in Three-Dimensional Cultures of Human Chondrocytes and Human Mesenchymal Stem Cells

Hypertrophic differentiation occurs during in vitro chondrogenesis of mesenchymal stem cells (MSCs), decreasing the quality of the cartilage construct. Previously we identified WNT pathway antagonists Dickkopf 1 homolog (DKK1) and frizzled-related protein (FRZB) as key factors in blocking hypertroph...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Stem Cells Dev
Päätekijät: Zhong, Leilei, Huang, Xiaobin, Rodrigues, Emilie Dooms, Leijten, Jeroen C.H., Verrips, Theo, El Khattabi, Mohamed, Karperien, Marcel, Post, Janine N.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Mary Ann Liebert, Inc. 2016
Aiheet:
Original Research Reports
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124737/
https://ncbi.nlm.nih.gov/pubmed/27733096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2016.0222
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia