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The Regulatory Role of Signaling Crosstalk in Hypertrophy of MSCs and Human Articular Chondrocytes

Hypertrophic differentiation of chondrocytes is a main barrier in application of mesenchymal stem cells (MSCs) for cartilage repair. In addition, hypertrophy occurs occasionally in osteoarthritis (OA). Here we provide a comprehensive review on recent literature describing signal pathways in the hype...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Zhong, Leilei, Huang, Xiaobin, Karperien, Marcel, Post, Janine N.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581295/
https://ncbi.nlm.nih.gov/pubmed/26287176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160819225
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