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The Regulatory Role of Signaling Crosstalk in Hypertrophy of MSCs and Human Articular Chondrocytes

Hypertrophic differentiation of chondrocytes is a main barrier in application of mesenchymal stem cells (MSCs) for cartilage repair. In addition, hypertrophy occurs occasionally in osteoarthritis (OA). Here we provide a comprehensive review on recent literature describing signal pathways in the hype...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Int J Mol Sci
Prif Awduron: Zhong, Leilei, Huang, Xiaobin, Karperien, Marcel, Post, Janine N.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581295/
https://ncbi.nlm.nih.gov/pubmed/26287176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160819225
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