GREM1, FRZB and DKK1 mRNA levels correlate with osteoarthritis and are regulated by osteoarthritis-associated factors

INTRODUCTION: Osteoarthritis is, at least in a subset of patients, associated with hypertrophic differentiation of articular chondrocytes. Recently, we identified the bone morphogenetic protein (BMP) and wingless-type MMTV integration site (WNT) signaling antagonists Gremlin 1 (GREM1), frizzled-rela...

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Main Authors: Leijten, Jeroen CH, Bos, Steffan D, Landman, Ellie BM, Georgi, Nicole, Jahr, Holger, Meulenbelt, Ingrid, Post, Janine N, van Blitterswijk, Clemens A, Karperien, Marcel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978825/
https://ncbi.nlm.nih.gov/pubmed/24286177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4306
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