Differential modulation of FXR activity by chlorophacinone and ivermectin analogs

Chemicals that alter normal function of farnesoid X receptor (FXR) have been shown to affect the homeostasis of bile acids, glucose, and lipids. Several structural classes of environmental chemicals and drugs that modulated FXR transactivation were previously identified by quantitative high-throughp...

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: Hsu, Chia-Wen, Hsieh, Jui-Hua, Huang, Ruili, Pijnenburg, Dirk, Khuc, Thai, Hamm, Jon, Zhao, Jinghua, Lynch, Caitlin, van Beuningen, Rinie, Chang, Xiaoqing, Houtman, Rene, Xia, Menghang
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124510/
https://ncbi.nlm.nih.gov/pubmed/27773686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2016.10.017
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