Differential modulation of FXR activity by chlorophacinone and ivermectin analogs

Chemicals that alter normal function of farnesoid X receptor (FXR) have been shown to affect the homeostasis of bile acids, glucose, and lipids. Several structural classes of environmental chemicals and drugs that modulated FXR transactivation were previously identified by quantitative high-throughp...

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Dettagli Bibliografici
Pubblicato in:Toxicol Appl Pharmacol
Autori principali: Hsu, Chia-Wen, Hsieh, Jui-Hua, Huang, Ruili, Pijnenburg, Dirk, Khuc, Thai, Hamm, Jon, Zhao, Jinghua, Lynch, Caitlin, van Beuningen, Rinie, Chang, Xiaoqing, Houtman, Rene, Xia, Menghang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124510/
https://ncbi.nlm.nih.gov/pubmed/27773686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2016.10.017
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