Differential modulation of FXR activity by chlorophacinone and ivermectin analogs

Chemicals that alter normal function of farnesoid X receptor (FXR) have been shown to affect the homeostasis of bile acids, glucose, and lipids. Several structural classes of environmental chemicals and drugs that modulated FXR transactivation were previously identified by quantitative high-throughp...

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Vydáno v:Toxicol Appl Pharmacol
Hlavní autoři: Hsu, Chia-Wen, Hsieh, Jui-Hua, Huang, Ruili, Pijnenburg, Dirk, Khuc, Thai, Hamm, Jon, Zhao, Jinghua, Lynch, Caitlin, van Beuningen, Rinie, Chang, Xiaoqing, Houtman, Rene, Xia, Menghang
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5124510/
https://ncbi.nlm.nih.gov/pubmed/27773686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2016.10.017
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