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Identification of Estrogen-Related Receptor α Agonists in the Tox21 Compound Library
The estrogen-related receptor α (ERRα) is an orphan nuclear receptor (NR) that plays a role in energy homeostasis and controls mitochondrial oxidative respiration. Increased expression of ERRα in certain ovarian, breast, and colon cancers has a negative prognosis, indicating an important role for ER...
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| Udgivet i: | Endocrinology |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Endocrine Society
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5774247/ https://ncbi.nlm.nih.gov/pubmed/29216352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00658 |
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