Identification of Estrogen-Related Receptor α Agonists in the Tox21 Compound Library

The estrogen-related receptor α (ERRα) is an orphan nuclear receptor (NR) that plays a role in energy homeostasis and controls mitochondrial oxidative respiration. Increased expression of ERRα in certain ovarian, breast, and colon cancers has a negative prognosis, indicating an important role for ER...

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Vydáno v:Endocrinology
Hlavní autoři: Lynch, Caitlin, Zhao, Jinghua, Huang, Ruili, Kanaya, Noriko, Bernal, Lauren, Hsieh, Jui-Hua, Auerbach, Scott S., Witt, Kristine L., Merrick, B. Alex, Chen, Shiuan, Teng, Christina T., Xia, Menghang
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2017
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Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774247/
https://ncbi.nlm.nih.gov/pubmed/29216352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00658
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