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Bloom’s Syndrome: Why Not Premature Aging? A comparison of the BLM and WRN helicases
Genomic instability is a hallmark of cancer and aging. Premature aging (progeroid) syndromes are often caused by mutations in genes whose function is to ensure genomic integrity. The RecQ family of DNA helicases is highly conserved and plays crucial roles as genome caretakers. In human, mutations in...
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| Publié dans: | Ageing Res Rev |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5124422/ https://ncbi.nlm.nih.gov/pubmed/27238185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2016.05.010 |
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