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Fanconi anemia and Bloom's syndrome crosstalk through FANCJ-BLM helicase interaction

Fanconi anemia (FA) and Bloom's syndrome (BS) are rare hereditary chromosomal instability disorders. FA displays bone marrow failure, acute myeloid leukemia, and head and neck cancers, whereas BS is characterized by growth retardation, immunodeficiency, and a wide spectrum of cancers. The BLM g...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Suhasini, Avvaru N., Brosh, Robert M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3249464/
https://ncbi.nlm.nih.gov/pubmed/22024395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tig.2011.09.003
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