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Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome

Bloom's syndrome (BS) and Fanconi anemia (FA) are autosomal recessive disorders characterized by cancer and chromosomal instability. BS and FA group J arise from mutations in the BLM and FANCJ genes, respectively, which encode DNA helicases. In this work, FANCJ and BLM were found to interact ph...

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Detalhes bibliográficos
Main Authors: Suhasini, Avvaru N, Rawtani, Nina A, Wu, Yuliang, Sommers, Joshua A, Sharma, Sudha, Mosedale, Georgina, North, Phillip S, Cantor, Sharon B, Hickson, Ian D, Brosh, Robert M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3041957/
https://ncbi.nlm.nih.gov/pubmed/21240188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.362
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