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Bloom’s Syndrome: Why Not Premature Aging? A comparison of the BLM and WRN helicases
Genomic instability is a hallmark of cancer and aging. Premature aging (progeroid) syndromes are often caused by mutations in genes whose function is to ensure genomic integrity. The RecQ family of DNA helicases is highly conserved and plays crucial roles as genome caretakers. In human, mutations in...
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| Publicado no: | Ageing Res Rev |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5124422/ https://ncbi.nlm.nih.gov/pubmed/27238185 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.arr.2016.05.010 |
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