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Cdc24 Is Essential for Long-range End Resection in the Repair of Double-stranded DNA Breaks

Double-stranded DNA breaks (DSBs) are highly detrimental DNA lesions, which may be repaired by the homologous recombination-mediated repair pathway. The 5′ to 3′ direction of long-range end resection on one DNA strand, in which 3′-single-stranded DNA overhangs are created from broken DNA ends, is an...

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Publié dans:J Biol Chem
Auteurs principaux: Zhang, Huimin, Hua, Yu, Li, Rui, Kong, Daochun
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5122767/
https://ncbi.nlm.nih.gov/pubmed/27729451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.755991
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