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Inhibition of NF-kappa B pathway leads to deregulation of epithelial-mesenchymal transition and neural invasion in pancreatic cancer

NF-κB plays an essential role in the initiation and progression of pancreatic cancer and specifically mediates the induction of epithelial-mesenchymal transition and invasiveness. In this study we demonstrate the importance of activated NF-κB signaling in EMT induction, lymphovascular metastasis, an...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Lab Invest
Hauptverfasser: Nomura, Alice, Majumder, Kaustav, Giri, Bhuwan, Dauer, Patricia, Dudeja, Vikas, Roy, Sabita, Banerjee, Sulagna, Saluja, Ashok K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5121017/
https://ncbi.nlm.nih.gov/pubmed/27775688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2016.109
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