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Modulation of post-translational modifications in β-catenin and LRP6 inhibits Wnt signaling pathway in pancreatic cancer

β-Catenin/Wnt signaling pathway is critically regulated in a normal cell by a number of post-translational modifications. In pancreatic cancer however, aberrant activation of this pathway plays a significant role in tumor progression and metastasis. Though a number of studies have focused on underst...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Garg, Bharti, Giri, Bhuwan, Majumder, Kaustav, Dudeja, Vikas, Banerjee, Sulagna, Saluja, Ashok
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8005332/
https://ncbi.nlm.nih.gov/pubmed/27919787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2016.11.026
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