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Heat Shock Protein 70 in Pancreatic Diseases: Friend or Foe
The heat shock response in pancreatitis that is activated via HSP70 protects acinar cells through multiple simultaneous mechanisms. It inhibits trypsinogen activation and modulates NF-κB signaling to limit acinar cell injury. On the other hand, HSP70 is overexpressed in pancreatic cancer and is hija...
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| Publicado no: | J Surg Oncol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5714583/ https://ncbi.nlm.nih.gov/pubmed/28543919 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jso.24653 |
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