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Minnelide Overcomes Oxaliplatin Resistance by Downregulating DNA Repair Pathway in Pancreatic Cancer
INTRODUCTION: Oxaliplatin is part of pancreatic cancer therapy in FOLFIRINOX or GEMOX/XELOX regimen. DNA damage repair is one of the factors responsible for oxaliplatin resistance that eventually develops in this cancer. Triptolide/Minnelide has been shown to be effective against pancreatic cancer i...
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| Publicado no: | J Gastrointest Surg |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4698020/ https://ncbi.nlm.nih.gov/pubmed/26503259 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11605-015-3000-3 |
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