Pre-clinical evaluation of Minnelide as a therapy for acute myeloid leukemia

BACKGROUND: There is an urgent need for novel and effective treatment options for acute myeloid leukemia (AML). Triptolide, a diterpenoid tri-epoxide compound isolated from the herb Tripterygium wilfordii and its water-soluble pro-drug-Minnelide have shown promising anti-cancer activity. A recent cl...

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Bibliografiska uppgifter
I publikationen:J Transl Med
Huvudupphovsmän: Giri, Bhuwan, Gupta, Vineet K., Yaffe, Brianna, Modi, Shrey, Roy, Pooja, Sethi, Vrishketan, Lavania, Shweta P., Vickers, Selwyn M., Dudeja, Vikas, Banerjee, Sulagna, Watts, Justin, Saluja, Ashok
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2019
Ämnen:
Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6528210/
https://ncbi.nlm.nih.gov/pubmed/31109340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-019-1901-8
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