Загрузка...

A phase I trial of panobinostat (LBH589) in patients with metastatic melanoma

Epigenetic alterations by histone/protein deacetylases (HDACs) are one of the many mechanisms that cancer cells use to alter gene expression and promote growth. HDAC inhibitors have proven to be effective in the treatment of specific malignancies, particularly in combination with other anticancer ag...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Cancer Med
Главные авторы: Ibrahim, Nageatte, Buchbinder, Elizabeth I., Granter, Scott R., Rodig, Scott J., Giobbie‐Hurder, Anita, Becerra, Carla, Tsiaras, Argyro, Gjini, Evisa, Fisher, David E., Hodi, F. Stephen
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119958/
https://ncbi.nlm.nih.gov/pubmed/27748045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.862
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!