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A phase I trial of panobinostat (LBH589) in patients with metastatic melanoma
Epigenetic alterations by histone/protein deacetylases (HDACs) are one of the many mechanisms that cancer cells use to alter gene expression and promote growth. HDAC inhibitors have proven to be effective in the treatment of specific malignancies, particularly in combination with other anticancer ag...
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| Опубликовано в: : | Cancer Med |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5119958/ https://ncbi.nlm.nih.gov/pubmed/27748045 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.862 |
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