ALKBH1-Mediated tRNA Demethylation Regulates Translation

Transfer RNA (tRNA) is a central component of protein synthesis and cell signaling network. One salient feature of tRNA is its heavily modified status, which can critically impact its function. Here we show that mammalian ALKBH1 is a tRNA demethylase. It mediates the demethylation of N(1)-methyladen...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell
Egile Nagusiak: Liu, Fange, Clark, Wesley, Luo, Guanzheng, Wang, Xiaoyun, Fu, Ye, Wei, Jiangbo, Wang, Xiao, Hao, Ziyang, Dai, Qing, Zheng, Guanqun, Ma, Honghui, Han, Dali, Evans, Molly, Klungland, Arne, Pan, Tao, He, Chuan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119773/
https://ncbi.nlm.nih.gov/pubmed/27745969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.09.038
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