ALKBH4-dependent demethylation of actin regulates actomyosin dynamics

Regulation of actomyosin dynamics by post-transcriptional modifications in cytoplasmic actin is still poorly understood. Here we demonstrate that dioxygenase ALKBH4-mediated demethylation of a monomethylated site in actin (K84me1) regulates actin–myosin interaction and actomyosin-dependent processes...

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Detalhes bibliográficos
Main Authors: Li, Ming-Ming, Nilsen, Anja, Shi, Yue, Fusser, Markus, Ding, Yue-He, Fu, Ye, Liu, Bo, Niu, Yamei, Wu, Yong-Sheng, Huang, Chun-Min, Olofsson, Maria, Jin, Kang-Xuan, Lv, Ying, Xu, Xing-Zhi, He, Chuan, Dong, Meng-Qiu, Rendtlew Danielsen, Jannie M., Klungland, Arne, Yang, Yun-Gui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674258/
https://ncbi.nlm.nih.gov/pubmed/23673617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2863
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