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Pharmacokinetics of the Antischistosomal Lead Ozonide OZ418 in Uninfected Mice Determined by Liquid Chromatography-Tandem Mass Spectrometry

One of the major neglected tropical diseases, schistosomiasis, is currently treated and controlled with a single drug, praziquantel. The quest for an alternative drug is fueled by the lack of activity of praziquantel against juvenile Schistosoma worms and the fear of emerging resistance. The synthet...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Leonidova, Anna, Vargas, Mireille, Huwyler, Jörg, Keiser, Jennifer
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5119018/
https://ncbi.nlm.nih.gov/pubmed/27697760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02394-15
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