Aloe-emodin suppresses hypoxia-induced retinal angiogenesis via inhibition of HIF-1α/VEGF pathway

Background: Aloe-emodin (AE) has been reported to possess the antiangiogenic effect on laser induced choroidal neovascularization. AE inhibits the vessel formation in the zebrafish embryos. However, it is still unclear whether AE can alleviate neovascularization. Here, we investigated the inhibitory...

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Publicat a:Int J Biol Sci
Autors principals: Wu, Jianming, Ke, Xiao, Wang, Wei, Zhang, Hongcheng, Ma, Na, Fu, Wei, Zhao, Manxi, Gao, Xiaoping, Hao, Xiaofeng, Zhang, Zhirong
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118782/
https://ncbi.nlm.nih.gov/pubmed/27877088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.16334
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