Inhibition of Hypoxia-Induced Retinal Angiogenesis by Specnuezhenide, an Effective Constituent of Ligustrum lucidum Ait., through Suppression of the HIF-1α/VEGF Signaling Pathway

Specnuezhenide (SPN), one of the main ingredients of Chinese medicine “Nü-zhen-zi”, has anti-angiogenic and vision improvement effects. However, studies of its effect on retinal neovascularization are limited so far. In the present study, we established a vascular endothelial growth factor A (VEGFA)...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Wu, Jianming, Ke, Xiao, Fu, Wei, Gao, Xiaoping, Zhang, Hongcheng, Wang, Wei, Ma, Na, Zhao, Manxi, Hao, Xiaofeng, Zhang, Zhirong
Format: Artigo
Langue:Inglês
Publié: MDPI 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6272965/
https://ncbi.nlm.nih.gov/pubmed/28009852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules21121756
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