Aloe-emodin suppresses hypoxia-induced retinal angiogenesis via inhibition of HIF-1α/VEGF pathway

Background: Aloe-emodin (AE) has been reported to possess the antiangiogenic effect on laser induced choroidal neovascularization. AE inhibits the vessel formation in the zebrafish embryos. However, it is still unclear whether AE can alleviate neovascularization. Here, we investigated the inhibitory...

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Vydáno v:Int J Biol Sci
Hlavní autoři: Wu, Jianming, Ke, Xiao, Wang, Wei, Zhang, Hongcheng, Ma, Na, Fu, Wei, Zhao, Manxi, Gao, Xiaoping, Hao, Xiaofeng, Zhang, Zhirong
Médium: Artigo
Jazyk:Inglês
Vydáno: Ivyspring International Publisher 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118782/
https://ncbi.nlm.nih.gov/pubmed/27877088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.16334
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