Aloe-emodin suppresses hypoxia-induced retinal angiogenesis via inhibition of HIF-1α/VEGF pathway

Background: Aloe-emodin (AE) has been reported to possess the antiangiogenic effect on laser induced choroidal neovascularization. AE inhibits the vessel formation in the zebrafish embryos. However, it is still unclear whether AE can alleviate neovascularization. Here, we investigated the inhibitory...

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Detalhes bibliográficos
Publicado no:Int J Biol Sci
Main Authors: Wu, Jianming, Ke, Xiao, Wang, Wei, Zhang, Hongcheng, Ma, Na, Fu, Wei, Zhao, Manxi, Gao, Xiaoping, Hao, Xiaofeng, Zhang, Zhirong
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118782/
https://ncbi.nlm.nih.gov/pubmed/27877088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ijbs.16334
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