Formononetin, an active compound of Astragalus membranaceus (Fisch) Bunge, inhibits hypoxia-induced retinal neovascularization via the HIF-1α/VEGF signaling pathway

BACKGROUND: It has been reported that formononetin (FMN), one of the main ingredients from famous traditional Chinese medicine “Huang-qi” (Astragalus membranaceus [Fisch] Bunge) for Qi-tonifying, exhibits the effects of immunomodulation and tumor growth inhibition via antiangiogenesis. Furthermore,...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Wu, Jianming, Ke, Xiao, Ma, Na, Wang, Wei, Fu, Wei, Zhang, Hongcheng, Zhao, Manxi, Gao, Xiaoping, Hao, Xiaofeng, Zhang, Zhirong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5042190/
https://ncbi.nlm.nih.gov/pubmed/27729769
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S114022
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