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Identification of inhibitors that dually target the new permeability pathway and dihydroorotate dehydrogenase in the blood stage of Plasmodium falciparum

Plasmodium parasites are responsible for the devastating disease malaria that affects hundreds of millions of people each year. Blood stage parasites establish new permeability pathways (NPPs) in infected red blood cell membranes to facilitate the uptake of nutrients and removal of parasite waste pr...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Dickerman, Benjamin K., Elsworth, Brendan, Cobbold, Simon A., Nie, Catherine Q., McConville, Malcolm J., Crabb, Brendan S., Gilson, Paul R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5118696/
https://ncbi.nlm.nih.gov/pubmed/27874068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep37502
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