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Decoupling Activation of Heme Biosynthesis from Anaerobic Toxicity in a Molecule Active in Staphylococcus aureus

Small molecules active in the pathogenic bacterium Staphylococcus aureus are valuable tools for the study of its basic biology and pathogenesis, and many molecules may provide leads for novel therapeutics. We have previously reported a small molecule, 1, which activates endogenous heme biosynthesis...

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Detalles Bibliográficos
Publicado en:ACS Chem Biol
Main Authors: Dutter, Brendan F., Mike, Laura A., Reid, Paul R., Chong, Katherine M., Ramos-Hunter, Susan J., Skaar, Eric P., Sulikowski, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117894/
https://ncbi.nlm.nih.gov/pubmed/26890615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00934
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