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Decoupling Activation of Heme Biosynthesis from Anaerobic Toxicity in a Molecule Active in Staphylococcus aureus

Small molecules active in the pathogenic bacterium Staphylococcus aureus are valuable tools for the study of its basic biology and pathogenesis, and many molecules may provide leads for novel therapeutics. We have previously reported a small molecule, 1, which activates endogenous heme biosynthesis...

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Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Dutter, Brendan F., Mike, Laura A., Reid, Paul R., Chong, Katherine M., Ramos-Hunter, Susan J., Skaar, Eric P., Sulikowski, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5117894/
https://ncbi.nlm.nih.gov/pubmed/26890615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.5b00934
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